LeSage, Gene D.: шукати на сайті Z-Library

Рік:

1989

Мова:

english

Файл:

PDF, 517 KB

english, 1989

Secretin activation of the apical Na+-dependent bile acid transporter is associated with cholehepatic shunting in rats

Gianfranco Alpini, Shannon Glaser, Leonardo Baiocchi, Heather Francis, Xuefeng Xia, Gene LeSage

Журнал:

Рік:

2005

Мова:

english

Файл:

PDF, 439 KB

english, 2005

Acute carbon tetrachloride feeding selectively damages large, but not small, cholangiocytes from normal rat liver

Gene D. LeSage, Antonio Benedetti, Shannon Glaser, Luca Marucci, Ziga Tretjak, Alessandra Caligiuri, Rebecca Rodgers, Jo Lynne Phinizy, Leonardo Baiocchi, Heather Francis, John Lasater, Laura Ugili, G

Журнал:

Noriatsu Kanno, Gene LeSage, Shannon Glaser, Domenico Alvaro, Assistant Professor Gianfranco Alpini

Рік:

1999

Мова:

english

Файл:

PDF, 886 KB

english, 1999

Functional heterogeneity of the intrahepatic biliary epithelium

Журнал:

Bioorganic & Medicinal Chemistry

Рік:

2000

Мова:

english

Файл:

PDF, 241 KB

english, 2000

Synthetic resveratrol aliphatic acid inhibits TLR2-mediated apoptosis and an involvement of Akt/GSK3β pathway

Lin Chen, Yi Zhang, Xiuli Sun, Hui Li, Gene LeSage, Avani Javer, Xiumei Zhang, Xinbing Wei, Yulin Jiang, Deling Yin

Журнал:

Рік:

2009

Мова:

english

Файл:

PDF, 1.22 MB

english, 2009

Regulation of cholangiocyte proliferation

Gene LeSage, Shannon Glaser, Gianfranco Alpini

Журнал:

Liver International

Рік:

2001

Мова:

english

Файл:

PDF, 270 KB

english, 2001

β-Arrestin 2 regulates toll-like receptor 4-mediated apoptotic signalling through glycogen synthase kinase-3β

Hui Li, Xiuli Sun, Gene LeSage, Yi Zhang, Zhihou Liang, Jixiang Chen, Gregory Hanley, Lei He, Shenggang Sun, Deling Yin

Журнал:

Immunology

Рік:

2010

Мова:

english

Файл:

PDF, 348 KB

english, 2010

Evaluation of differential gene expression by microarray analysis in small and large cholangiocytes isolated from normal mice

Yoshiyuki Ueno, Gianfranco Alpini, Kaichiro Yahagi, Noriatsu Kanno, Yuki Moritoki, Koji Fukushima, Shannon Glaser, Gene LeSage, Tooru Shimosegawa

Журнал:

Liver International

Рік:

2003

Мова:

english

Файл:

PDF, 813 KB

english, 2003

Gastrin Inhibits Cholangiocyte Growth in Bile Duct–Ligated Rats by Interaction With Cholecystokinin-B/Gastrin Receptors viad -myo-Inositol 1,4,5-Triphosphate–, Ca2+-, and Protein Kinase C α–Dependent Mechanisms

Shannon Glaser, Antonio Benedetti, Luca Marucci, Domenico Alvaro, Leonardo Baiocchi, Noriatsu Kanno, Alessandra Caligiuri, Jo Lynne Phinizy, Usha Chowdury, Emanuela Papa, Gene LeSage, Gianfranco Alpin

Журнал:

Рік:

2000

Мова:

english

Файл:

PDF, 366 KB

english, 2000

Bile acid feeding increased proliferative activity and apical bile acid transporter expression in both small and large rat cholangiocytes

Gianfranco Alpini, Yoshiyuki Ueno, Shannon S. Glaser, Marco Marzioni, Jo Lynne Phinizy, Heather Francis, Gene LeSage

Журнал:

Рік:

2001

Мова:

english

Файл:

PDF, 337 KB

english, 2001

Stimulation of α2-adrenergic receptor inhibits cholangiocarcinoma growth through modulation of Raf-1 and B-Raf activities

Noriatsu Kanno, Gene LeSage, Jo Lynne Phinizy, Shannon Glaser, Heather Francis, Gianfranco Alpini

Журнал:

Рік:

2002

Мова:

english

Файл:

PDF, 375 KB

english, 2002

Insulin inhibits secretin-induced ductal secretion by activation of PKC alpha and inhibition of PKA activity

Gene D. LeSage, Luca Marucci, Domenico Alvaro, Shannon S. Glaser, Antonio Benedetti, Marco Marzioni, Tushar Patel, Heather Francis, Jo Lynne Phinizy, Gianfranco Alpini

Журнал:

Gene D. LeSage, Gary L. Davis

Рік:

2002

Мова:

english

Файл:

PDF, 390 KB

english, 2002

Book reviews

Журнал:

Digestive Diseases and Sciences

Рік:

1982

Мова:

english

Файл:

PDF, 106 KB

english, 1982

HIV-1 gp120 primes lymphocytes for opioid-induced, β-arrestin 2-dependent apoptosis

Jonathan Moorman, Yi Zhang, Bindong Liu, Gene LeSage, Yangchao Chen, Charles Stuart, Deborah Prayther, Deling Yin

Журнал:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Рік:

2009

Мова:

english

Файл:

PDF, 379 KB

english, 2009

Chronic stress promotes lymphocyte reduction through TLR2 mediated PI3K signaling in a β-arrestin 2 dependent manner

Hui Li, Lin Chen, Ying Zhang, Gene LeSage, Yi Zhang, Yan Wu, Gregory Hanley, Shenggang Sun, Deling Yin

Журнал:

Journal of Neuroimmunology

Рік:

2011

Мова:

english

Файл:

PDF, 532 KB

english, 2011

Toll-like receptor 2 is required for opioids-induced neuronal apoptosis

Yi Li, Hui Li, Yi Zhang, Xiuli Sun, Gregory A. Hanley, Gene LeSage, Ying Zhang, Shenggang Sun, Ying Peng, Deling Yin

Журнал:

Biochemical and Biophysical Research Communications

Рік:

2010

Мова:

english

Файл:

PDF, 1.31 MB

english, 2010

cAMP stimulates the secretory and proliferative capacity of the rat intrahepatic biliary epithelium through changes in the PKA/Src/MEK/ERK1/2 pathway

Heather Francis, Shannon Glaser, Yoshiyuki Ueno, Gene LeSage, Luca Marucci, Antonio Benedetti, Silvia Taffetani, Marco Marzioni, Domenico Alvaro, Julie Venter, Ramona Reichenbach, Giammarco Fava, Jo L

Журнал:

Рік:

2004

Мова:

english

Файл:

PDF, 457 KB

english, 2004

Essential role of toll-like receptor 2 in morphine-induced microglia activation in mice

Yi Zhang, Hui Li, Yi Li, Xiuli Sun, Mengyang Zhu, Gregory Hanley, Gene LeSage, Deling Yin

Журнал:

Neuroscience Letters

Рік:

2011

Мова:

english

Файл:

PDF, 371 KB

english, 2011

Glycogen synthase kinase-3 and p38 MAPK are required for opioid-induced microglia apoptosis

Nanchang Xie, Hui Li, Dailin Wei, Gene LeSage, Lin Chen, Shengjun Wang, Yi Zhang, Lingyi Chi, Kenneth Ferslew, Lei He, Zhaofu Chi, Deling Yin

Журнал:

Neuropharmacology

Рік:

2010

Мова:

english

Файл:

PDF, 1.06 MB

english, 2010

α-1 adrenergic receptor agonists modulate ductal secretion of BDL rats via Ca2+- and PKC-dependent stimulation of cAMP

Gene D. LeSage, Domenico Alvaro, Shannon Glaser, Heather Francis, Luca Marucci, Tania Roskams, Jo Lynne Phinizy, Marco Marzioni, Antonio Benedetti, Silvia Taffetani, Barbara Barbaro, Giammarco Fava, Y

Журнал:

Рік:

2004

Мова:

english

Файл:

PDF, 566 KB

english, 2004

Bile acid feeding induces cholangiocyte proliferation and secretion: Evidence for bile acid–regulated ductal secretion

Gianfranco Alpini*, ‡, §, Shannon S. Glaser*, Yoshiyuki Ueno¶, Rebecca Rodgers*, Jo Lynne Phinizy*, Heather Francis*, Leonardo Baiocchi*, Leigh A. Holcomb§, ∥, Alessandra Caligiuri*, Gene D. LeSage*

Журнал:

Рік:

1999

Мова:

english

Файл:

PDF, 265 KB

english, 1999

Cholinergic system modulates growth, apoptosis, and secretion of cholangiocytes from bile duct–ligated rats

Gene LeSage*, Domenico Alvaro‡, Antonio Benedetti§, Shannon Glaser∥, Luca Marucci§, Leonardo Baiocchi¶, Wendy Eisel#, Alessandra Caligiuri*, Jo Lynne Phinizy∥, Rebecca Rodgers¶, Heather Francis∥, Gian

Журнал:

Рік:

1999

Мова:

english

Файл:

PDF, 256 KB

english, 1999

Taurohyodeoxycholate- and tauroursodeoxycholate-induced hypercholeresis is augmented in bile duct ligated rats

Leonardo Baiocchi, Gianfranco Alpini, Shannon Glaser, Mario Angelico, Domenico Alvaro, Heather Francis, Marco Marzioni, Jo Lynne Phinizy, Barbara Barbaro, Gene LeSage

Журнал:

Рік:

2003

Мова:

english

Файл:

PDF, 405 KB

english, 2003

Gamma-interferon inhibits secretin-induced choleresis and cholangiocyte proliferation in a murine model of cirrhosis

Gianfranco Alpini, Ivan Elias, Shannon S. Glaser, Rebecca E.D. Rodgers, Jo Lynne Phinizy, Willie E. Robertson, Heather Francis, John Lasater, Mark Richards, Gene D. LeSage

Журнал:

Leonardo Baiocchi, Gene LeSage, Shannon Glaser, Gianfranco Alpini

Рік:

1997

Мова:

english

Файл:

PDF, 1.29 MB

english, 1997

Regulation of cholangiocyte bile secretion

Журнал:

Рік:

1999

Мова:

english

Файл:

PDF, 1.66 MB

english, 1999

Gastrin reverses established cholangiocyte proliferation and enhanced secretin-stimulated ductal secretion of BDL rats by activation of apoptosis through increased expression of Ca2+-dependent PKC isoforms

Shannon Glaser, Domenico Alvaro, Yoshiyuki Ueno, Heather Francis, Marco Marzioni, Jo Lynne Phinizy, Brandy Baumann, Maria Grazia Mancino, Julie Venter, Gene LeSage, Gianfranco Alpini

Журнал:

Liver International

Рік:

2003

Мова:

english

Файл:

PDF, 244 KB

english, 2003

Ursodeoxycholate and tauroursodeoxycholate inhibit cholangiocyte growth and secretion of BDL rats through activation of PKC alpha

Gianfranco Alpini, Leonardo Baiocchi, Shannon Glaser, Yoshiyuki Ueno, Marco Marzioni, Heather Francis, Jo Lynne Phinizy, Mario Angelico, Gene LeSage

Журнал:

Рік:

2002

Мова:

english

Файл:

PDF, 471 KB

english, 2002

Liver X receptor β and peroxisome proliferator-activated receptor δ regulate cholesterol transport in murine cholangiocytes

Xia, Xuefeng, Jung, Dongju, Webb, Paul, Zhang, Aijun, Zhang, Bin, Li, Lifei, Ayers, Stephen D., Gabbi, Chiara, Ueno, Yoshiyuki, Gustafsson, Jan-Åke, Alpini, Gianfranco, Moore, David D., LeSage, Gene D

Журнал:

Рік:

2012

Мова:

english

Файл:

PDF, 1.02 MB

english, 2012

Bile acid stimulation of small bile duct proliferation requires de novo expression of the apical bile acid transporter (ABAT)

Gianfranco Alpini, Shannon Glaser, Jo Lynne Phinizy, Noriatsu Kanno, Heather Francis, Mikel Ludvik, Gene Lesage

Журнал:

Рік:

2001

Мова:

english

Файл:

PDF, 189 KB

english, 2001

Regulation of cholanglocyte apical bile acid transporter (ABAT) activity by biliary bile acids: Different potential compensatory changes for intrahepatic and extrahepatic cholestasis

Gianfranco Alpini, Shannon Glaser, Jo Lynne Phinizy, Noriatsu Kanno, Heather Francis, Mikel Ludvik, Gene Lesage

Журнал:

Рік:

2001

Мова:

english

Файл:

PDF, 176 KB

english, 2001

The growth of two human cholangiocarcinoma cell lines is inhibited by alpha-2 adrenergic agonists by a cAMP-dependent mechanism through the inhibition of Raf-1 and MAPK systems

Noriatsu Kanno, Gene Lesage, Shannon Glaser, Jo Lynne Phinizy, Mikel Ludvik, Gianfranco Alpini

Журнал:

Рік:

2001

Мова:

english

Файл:

PDF, 187 KB

english, 2001

CDC42 is Required for Intestinal Stem Cell Self-Renewal but Not Differentiation

Lei Chen, Gene LeSage

Журнал:

Рік:

2011

Мова:

english

Файл:

PDF, 43 KB

english, 2011

Gastrin inhibits cholangiocarcinoma growth through increased apoptosis by activation of Ca2+-dependent protein kinase C-α

Noriatsu Kanno, Shannon Glaser, Usha Chowdhury, Jo Lynne Phinizy, Leonardo Baiocchi, Heather Francis, Gene LeSage, Gianfranco Alpini

Журнал:

Рік:

2001

Мова:

english

Файл:

PDF, 1.28 MB

english, 2001

856 Bile acid feeding protects cholangiocytes from hepatic artery ligation-induced apoptosis by stimulating cholangiocyte VEGF secretion through a PI3K/AKT dependent mechanism

Shannon Glaser, Heather Francis, Silvia Taffetani, Jo Lynne Phinizy, Domenico Alvaro, Eugenio Gaudio, Trenton Horst, Marco Marzioni, Gene LeSage, Brandy Baumann, Julie Venter, Giammarco Fava, Yoshiyuk

Журнал:

Рік:

2003

Мова:

english

Файл:

PDF, 255 KB

english, 2003

Bile acid depletion and repletion regulate cholangiocyte growth and secretion by a phosphatidylinositol 3-kinase–dependent pathway in rats

Gianfranco Alpini, Shannon Glaser, Domenico Alvaro, Yoshiyuki Ueno, Marco Marzioni, Heather Francis, Leonardo Baiocchi, Tonino Stati, Barbara Barbaro, Jo Lynne Phinizy, Jeremy Mauldin, Gene LeSage

Журнал:

Рік:

2002

Мова:

english

Файл:

PDF, 460 KB

english, 2002

Cyclic AMP Regulates Bicarbonate Secretion in Cholangiocytes Through Release of ATP Into Bile

Noritaka Minagawa, Jun Nagata, Kazunori Shibao, Anatoliy I. Masyuk, Dawidson A. Gomes, Michele A. Rodrigues, Gene Lesage, Yasutada Akiba, Jonathan D. Kaunitz, Barbara E. Ehrlich, Nicholas F. Larusso,

Журнал:

Brain, Behavior, and Immunity

Рік:

2007

Мова:

english

Файл:

PDF, 3.25 MB

english, 2007

Essential role of IL-10/STAT3 in chronic stress-induced immune suppression

Hu, Dan, Wan, Lei, Chen, Michael, Caudle, Yi, LeSage, Gene, Li, Qinchuan, Yin, Deling

Журнал:

Рік:

2014

Мова:

english

Файл:

PDF, 1.92 MB

english, 2014

FXR-induced secretion of FGF15/19 inhibits CYP27 expression in cholangiocytes through p38 kinase pathway

Jung, Dongju, York, J. Philippe, Wang, Li, Yang, Chaofeng, Zhang, Aijun, Francis, Heather L., Webb, Paul, McKeehan, Wallace L., Alpini, Gianfranco, LeSage, Gene D., Moore, David D., Xia, Xuefeng

Журнал:

Pflügers Archiv European Journal of Physiology

Рік:

2014

Мова:

english

Файл:

PDF, 1.11 MB

english, 2014

Cost-of-illness for hepatitis C patients is greater than baseline medical costs and increases with disease severity

Ghaleb, Aline, Sherer, Atkinson, Burk, Kimberley, Culp, Kim, Lesage, Gene

Журнал:

Alpini, Gianfranco, Glaser, Shannon, Phinizy, Jo Lynne, Hofmann, Alan F., LeSage, Gene

Рік:

2000

Мова:

english

Файл:

PDF, 175 KB

english, 2000

Bile acid absorption in isolated bile duct units (IBDU) is primarily due to the apical bile acid transporter

Журнал:

NAGORNEY, DAVID M., LeSAGE, GENE D., CHARBONEAU, J. WILLIAM, McGOUGH, PAUL F.

Рік:

2000

Мова:

english

Файл:

PDF, 199 KB

english, 2000

Cystadenoma of the Proximal Common Hepatic Duct: The Use of Abdominal Ultrasonography and Transhepatic Cholangiography in Diagnosis

Журнал:

Mayo Clinic Proceedings

Рік:

1984

Мова:

english

Файл:

PDF, 548 KB

english, 1984

Camp stimulates secretory and proliferative capacity of the rat intrahepatic biliary epithelium through the PKA system

LeSage, Gene, Glaser, Shannon, Alvaro, Domenico, Kanno, Noriatsu, Phinizy, Jo Lynne, Chowdury, Usha, Alpini, Gianfranco

Журнал:

Kanno, Noriatsu, Glaser, Shannon, Chowdhury, Usha, Phinizy, Jo Lynne, Francis, Heather, LeSage, Gene, Alpini, Gianfranco

Рік:

2000

Мова:

english

Файл:

PDF, 201 KB

english, 2000

The alpha-2 adrenergic agonist, UK 14,304, inhibits growth andincreases apoptosis of the cholangio-carcinoma cell line, Mz-Cha-1, through camp but not Ca2+-dependent mechanisms

Журнал:

Рік:

2000

Мова:

english

Файл:

PDF, 199 KB

english, 2000

Autocrine TGF-beta signaling in cholangiocytes reduces impaired bile duct repair due to TNF

Xia, Xuefeng, Shentu, Shujun, Roundtree, Marlon, Najam, Azmeena, Lesage, Gene

Журнал:

Phinizy, Jo Lynne, Glaser, Shannon, Francis, Heather, Kanno, Noriatsu, Chowdhury, Usha, Alpini, Gianfranco, LeSage, Gene

Рік:

2003

Мова:

english

Файл:

PDF, 257 KB

english, 2003

Development and characterization of secretory functions of a rat cholangiocyte cell culture system

Журнал:

Рік:

2000

Мова:

english

Файл:

PDF, 186 KB

english, 2000

D2 but not D1 dopaminergic agonists inhibit secretory processes of the intrahepatic biliary epithelium through a PKC-dependent mechanism

Glaser, Shannon, Phinizy, Jo Lynne, Chowdhury, Usha, Kanno, Noriatsu, Francis, Heatber, Ueno, Yoshiyuki, Alvaro, Domenico, Lesage, Gene

Журнал:

Kanno, Noriatsu, Glaser, Shannon, Phinizy, Jo Lynne, Chowdhury, Usha, Francis, Heather, Alpini, Gianfranco, LeSage, Gene

Рік:

2000

Мова:

english

Файл:

PDF, 201 KB

english, 2000

Inhibition of cholangiocarcinoma growth by tauroursodeoxycholic acid requires activation of cah2+ and protein kinase c (PKC) signaling pathways

Журнал:

Рік:

2000

Мова:

english

Файл:

PDF, 196 KB

english, 2000

Efficacy of hepatitis C treatment is a function of ethnicity

Nguyen, Duke D.H., Basu, Dhiman, Clark, Cinda, Lesage, Gene

Журнал:

Рік:

2003

Мова:

english

Файл:

PDF, 182 KB

english, 2003

171 Loss of Nm23-H2 and Ncor Interactions with Peroxisome Proliferator-Activated Receptor δ (PPARδ) Promotes Cholangiocarcinoma Growth

Xia, Xuefeng, Zhang, Wenzheng, Venugopsl, Sushma, Xiao, Yuhua, Gao, Dongbing, LeSage, Gene

Журнал:

Рік:

2008

Мова:

english

Файл:

PDF, 65 KB

english, 2008

Alpha-napthylisothiocyanate-induced cholangiocyte apoptosis is dependent on increased reactive oxygen species (ROS)

Lesage, Gene, Glaser, Shannon, Francis, Heather, Ludvik, Mikel, Phinizy, Jo Lynne, Kanno, Noriatsu, Alpini, Gianfranco

Журнал: